Dangers and risks of Statin Medications

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Statin medications include Lipitor, Zocor, Prevastin and more.  They are generally given to individuals with a total cholesterol level of over 200 but lately even those with cholesterol levels at 170 are prescribed these medications.  There is much evidence coming to light to suggest these drugs are not only ineffective for preventing heart attack but may have many undesirable side effects.

Book review: How Statin Drugs Really Lower Cholesterol and Kill You One Cell at a Time
by James B. Yoseph and Hannah Yoseph, MD
(Self published)

Information in this book includes the following:

Early statin research was carried out by Sankyo in Japan and Merck in the United States. In the early studies, the research was halted when all the lab animals developed cancer. The research also clearly showed that statins work by disrupting the mevalonate pathway which may interfere with DNA replication, causing the death of the cell.

Brown and Goldstein, two of the main researchers for Merck, wrote a treatise explaining how statins lower cholesterol and won a Nobel prize. Glaringly lacking in their paper were the side effects of statin drugs.

The authors of the above book, feel that medical providers who prescribe statins are either lacking in knowledge about the medications or pandering to "the establishment".  Truth be known, most providers due to lack of time, end up using the pharmaceutical seminars for their continuing education credits (CME's).  These pharmaceutical companies wine and dine the providers while providing intense seminars which are very biased in favor of the featured medication or treatment and greatly lacking in providing a true picture of the side effects and downside of the products. 

The authors of the book suggest that a conflict of interest has motivated some pharmaceutical companies to misbehave in a number of lawsuit cases that are a matter of public record.

The NIH-backed National Cholesterol Education Program (NCEP) set national policy for lowering cholesterol with statins. Sadly, those doctors on the committee establishing these guidelines had financial relationships with those pharmaceutical companies benefiting from the sale of statin drugs.

In an advisory committee meeting held to review guidelines for lovastatin, the meeting was not chaired by an FDA employee but by a Merck consultant. The advisory committee included two Merck consultants and seven Merck employees. Half of the audience was made up of Merck consultants.

Finally, the Japanese researcher Dr. Akira Endo, credited with finding the first statin, refused to take the medication for his high cholesterol. When queried about this, he replied with a Japanese proverb, "The indigo dyer wears white trousers." To make sense of that you need to know indigo dye is toxic.

Since the book was written, many more side effects of statin drugs have been observed, including rather significantly raising the risk for cancer.  However, despite all this, some nine million people worldwide, take statin drugs on a regular basis.  So it remains a "cash cow" for the manufacturers.

Detailed article - How statins really lower cholesterol

Co. 2013